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Endocarditis Algorithm - Infective vs Noninfective Causes Noninfective: • Malignancy • Autoimmune disease • Systemic infection Native Valve - Acute: • Staphylococcus aureus • Non—viridans streptococci • Staphylococcus lugdunensis Native Valve - Subacute: • Viridans streptococci • Enterococcus • Streptococcus gallolyticus • Staphylococcus epidermidis • HACEK • Culture-negative Prosthetic Valve - Early: • Staphylococcus aureus • Staphylococcus epidermidis • Gram-negative bacilli • Fungi • Diphtheroids Prosthetic Valve - Late: • Viridans streptococci • Staphylococcus aureus • Staphylococcus epidermidis • Enterococcus • Non-viridans streptococci IVDU: • Staphylococcus aureus • Streptococcus • Enterococcus • Gram-negative bacilli • Fungi Dr. André Mansoor @AndreMansoor - Author of Frameworks for Internal Medicine https://amzn.to/2LmUODZ #Endocarditis #Algorithm #Infective #Noninfective #Causes #Differential #Diagnosis