REBEL Review 99: Serotonin Syndrome via Yosuf Alam, MSIV Presentation: Altered mentd status, Seizures, Myoclonus, Hypertension, Hyperthermia (most common cause of death), Hyperreflexia, Muscle rigidity (Lower extremity Upper extremity) Diagnosis: Clinical! No confirmatory lab tests Cornerstone of treatment is discontinuing all serotonergic drugs and providing appropriate supportive care: • IV fluid hydration; evaluation for rhabdomyolysis • External cooling measures for hyperthermia #SerotoninSyndrome #management #toxicology #REBELEM #diagnosis
