Adverse Effects of NSAIDs
Prostaglandins decreased
- Gastric mucosal damage with ulcer formation, bleeding, and perforation
- Nephropathy, decreased excretion of NaCl and H2O, edemas, increased blood pressure, impaired wound healing, diarrhea, disturbed uterine motility
Leukotrienes increased
- Bronchoconstriction, bronchial asthma, proinflammatory effect
#NSAIDs #AdverseEffects #SideEffects #Pharmacology