Adverse Effects of NSAIDs Prostaglandins decreased - Gastric mucosal damage with ulcer formation, bleeding, and perforation - Nephropathy, decreased excretion of NaCl and H2O, edemas, increased blood pressure, impaired wound healing, diarrhea, disturbed uterine motility Leukotrienes increased - Bronchoconstriction, bronchial asthma, proinflammatory effect #NSAIDs #AdverseEffects #SideEffects #Pharmacology