Characteristics of Serotonin Syndrome and Other Hyperthermic Syndromes Serotonin Syndrome - SSRIs, second-generation antidepressants, MAOIs, linezolid, tramadol, meperidine, fentanyl, ondansetron, sumatriptan - Hypertension, hyperreflexia, tremor,clonus, hyperthermia, hyperactive bowel sounds, diarrhea, mydriasis, agitation Neuroleptic Malignant Syndrome - D2-blocking antipsychotics - Acute severe parkinsonism; hypertension, hyperthermia, normal or reduced bowel sounds; onset over 1-3 days Malignant hyperthermia - Volatile anesthetics, succinylcholine - Hyperthermia, muscle rigidity, hypertension, tachycardia; onset within minutes #Hyperthermic #Syndromes #Diagnosis #Comparison #Table #Serotonin
