Renal Effect of NSAIDs Inhibition of Prostaglandin Synthesis - Renal disease, Cardiovascular disease -> Decreased renal blood flow - Cirrhosis, Nephrosis, Heart failure, Diuretics -> Decreased blood volume -> Increased vasoconstrictors: Angiotensin II, Catecholamines, Vasopressin NSAlDs inhibit prostaglandin synthesis, leaving actions of Vasoconstrictors unopposed. #NSAIDs #Prostaglandins #Pharmacology #Pathophysiology
