Antisocial Personality Disorder (ASPD): Pathogenesis and Clinical Findings
Work & lnterpersonal:
 • Home Life Troubles - Conflict w. authority/parents, running away from home
 • School Problems - Peer fighting and poor academic performance
 • Poor Relationships - Unstable & abusive marriages with increased rate of separation/divorce
 • Work Problems - Poor performance, unreliable, irresponsible, frequent job changes/firings
Glib & Deceptive:
 • Distorted Persona - Superficially charming and grandiose sense of self-worth
 • Deceitfulness - Pathological lying and the use of aliases and manipulation for personal gain
 • Behaviour Rationalization - Victim blaming, minimizing the harmfulness of their behaviour, feel no remorse
Risk & Violence:
 • Unlawful and Violent Behaviour - Cruelty towards animals, other children, stealing, vandalism, fire setting (sometimes directed at own friends/family)
 • High Risk Behaviour - Impulsive drug use and sexual promiscuity with unsafe sexual practices
 • Aggression - Commits acts of physical assault

ASPD Mnemonic: CORRUPT
 - Conforming to law and social norms lacking
 - Obligations ignored
 - Reckless disregard of safety
 - Remorselessness
 - Underhanded, manipulative
 - Planning insufficient / imPulsive
 - Temper irritable and aggressive
Dx: >3 of above with patterns of behaviour since age 15 and evidence of conduct disorder prior to 15 yrs. Not exclusively within schizophrenia or bipolar disorder

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The Calgary Guide to Understanding Disease @TheCalgaryGuide · 4 years ago
Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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