Lung Nodule - Differential Diagnosis Algorithm
Nodule on > 2 Years Without a Change in Size:
• Scar
• Granuloma
• Arteriovenous Malformation
Solitary Nodule:
• Malignant Neoplasm
• Benign Neoplasm (eg. Hamartoma, Lipoma, Fibroma)
• Granuloma
• Abscess
• Arteriovenous Malformation
• Bronchogenic Cyst
• Rounded Atelectasis
Malignancy:
• Primary lung cancer
• Metastases ("cannonball lesions"; Eg. Melanoma, Head & Neck, Sarcoma, Colon, Kidney, Breast, Testicle)
Infection:
• Fungal
• Tuberculosis
• Septic Embolism
• Parasitic
Inflammation:
• Rheumatoid Arthritis
• Granulomatosis with polyangiitis (GPA) / microscopic polyangiitis (MPA)
• Sarcoidosis
• Pneumoconiosis
Vascular:
• Arteriovenous Malformation
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