Tumor lysis syndrome (TLS) - Pathophysiology:
→ Massive tumor cell lysis
→ Release of large amounts of K+, phosphate, and uric acid
→ Usually after initiating cytotoxic therapy of ALL, AML, NHL
→ AKI can result from deposition of uric acid and /or calcium phosphate crystals
#TumorLysis #syndrome #TLS #Pathophysiology