Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 β€’ Increases BP, SVR
 β€’ Risk of reflex bradycardia
β€’ Higher doses cause ... more alpha-effect ... V2 antidiuretic effect ... , less of a BP effect ... cAMP/cGMP β€’ Causes
Vasopressors Table 
Rough properties by Target Receptor, Heart Rate/Inotropy, Systemic Vascular Resistance, Cardiac Output, Blood Pressure,
Vasopressors Table ... Receptor, Heart Rate/Inotropy ... Resistance, Main Uses ... - Dopamine, low ... #Pharmacology #Effect
Cholinesterase Inhibitor (ChEl) and Memantine Deprescribing Algorithm 

To support health care professionals in employing the recommendations
Deprescribing Algorithm ... This algorithm helps ... decide when and how ... memantine safely and how ... to monitor effects
SSRI Initiation
How long before increasing dose?
 β€’ 4 wks. Initial response in 2-4 wks, max response
SSRI Initiation How ... Side effects? ... transient Gl upset (nausea ... libido, sexual side effects
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison

Composition of LR:
 β€’ Sodium 130 mEq/L
 β€’
- Protective effects ... shift β€’ Saline Causes ... decreased renal blood flow ... β€’ Saline May Cause ... #pharmacology #effects
Push Dose Pressors - Mixing Instructions.

EPINEPHRINE
Has alpha and beta 1/2 effects so it is an inopressor
Do
alpha and beta 1/2 effects ... 100 mcg/ml) β€’ Now ... so no intrinsic inotropy ... bag of NS β€’ Now
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... normal volume-based algorithm ... can be high or low ... Primary polydipsia), Low ... differential #diagnosis #table
COVID-19 - A Seattle Intensivist's One-Page Cheat-Sheet on COVID-19 v2.7 Updated March 26 2020

(v2.7) incorporating newer
COVID19 in the ICU, now ... (v2.5) It reflects ... v2.3) updated to reflect ... 31 β€’ First US case