Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest - TTM2 Visual Abstract https://www.nejm.org/doi/full/10.1056/NEJMoa2100591 Conclusion: In patients with coma after out-of-hospital cardiac arrest, targeted hypothermia did not lead to a lower incidence of death by 6 months than targeted normothermia. #Hypothermia #Normothermia #OHCA #Arrest #CardiacArrest #VisualAbstract #ems #TTM2

Characteristics, treatment, outcomes and cause of death of invasively ventilated patients with COVID-19 ARDS in Milan, Italy Infographic by Tommaso Scquizzato @tscquizzato Source for infographic: https://bit.ly/2SiXYgD IG: https://www.instagram.com/p/B_W6sOTKIBl/ FB: https://www.facebook.com/SRAnesthesiaICU/photos/a.109230977169262/219237669501925/ Case series of 73 mechanically ventilated #COVID19 patients with #ARDS in Milan, Italy with the longest follow-up. Mortality of ICU mechanically ventilated patients with COVID-19 ARDS is as high as 23% at the 20 days follow-up. Acute kidney injury (75%) and secondary bacteremia (37%) are the most frequent complications of COVID-19 ARDS. Also, pneumothorax, pneumomediastinum, and thromboembolic complications were relatively common. Hypertension, rapid disease progression, older age and low SpO2 at admission are predictors of mortality in COVID-19 patients admitted to the ICU. COVID-19 ARDS patients admitted to the ICU with early improvement in PaO2/FiO2 are more likely to survive. We were the first ones to notice that smokers are poorly represented among critically ill COVID-19 ARDS patients: selection bias? poor collection of medical history? protective effect of tobacco? At hospital admission, lymphocytopenia was present in 73% of COVID-19 patients and the median C-reactive protein was 184 mg/dL (IQR, 108.2–269.1 mg/dL).

Visual Abstract - Rocuronium vs. Succinylcholine for Pre-hospital Rapid Sequence Intubation JAMA. 2019;322(23):2303-2312. doi:10.1001/jama.2019.1825 https://jamanetwork.com/journals/jama/article-abstract/2757578 Useful commentary on the questionable conclusions of this study via @pulmcrit - https://emcrit.org/pulmcrit/rare-catastrophic-complications/ Article Conclusions: Among patients undergoing endotracheal intubation in an out-of-hospital emergency setting, rocuronium, compared with succinylcholine, failed to demonstrate noninferiority with regard to first-attempt intubation success rate. Visual Abstract by Tommaso Scquizzato @ https://twitter.com/tscquizzato #Rocuronium #Succinylcholine #VisualAbstract #Prehospital #EMS #RSI #Intubation #EBM

Data Science for Critical Care Masterclass at ESICM #LIVES2019 https://www.esicm.org/blog/?p=2231 The goal of this Data Science masterclass is to teach doctors and other health care professionals basic concepts and skills and give tools for working more effectively with data. Moreover, in the literature there is an increasing number of papers describing AI/machine learning algorithms and prediction models so clinicians and other healthcare provides must know the key concepts of Data Science to correctly interpret results. #DataScience #MachineLearning #CriticalCare

ECMO after EOLIA: what is next? Infographic by Tommaso Scquizzato (@tscquizzato) based on a presentation at #LIVES2019 ESICM by Alain Combes #ECMO #EOLIA #ARDS

Emergency Management of the agitated patient Infographic by Tommaso Scquizzato (@tscquizzato) based on a talk by Reuben Strayer at SMACCDUB #Agitation #EmergencyDepartment

To Board or Not To Board? Infographic by Tommaso Scquizzato (@tscquizzato) based on this review on RebelEM https://rebelem.com/spinal-immobilization-in-trauma-patients/ #EMS #SpinalImmobilization #Trauma

ESICM LIVES 2019 session on Post Cardiac Arrest Care. Summary and infographic by Tommaso Scquizzato (@tscquizzato): https://www.esicm.org/blog/?p=2337 Topics covered: TTM: where are we now? Coronary angiography: to whom and when? Heamodynamic management We need to monitor what and how? Patient outcome related to multi-organ failure Is there a place for Vitamin C? #TTM #CardiacArrest #CoronaryAngiography #STEMI #Heamodynamics #Monitoring #Outcomes #VitaminC

Volatile Anesthetics versus Total Intravenous Anesthesia for Cardiac Surgery N Engl J Med 2019; 380:1214-1225 DOI: 10.1056/NEJMoa1816476 CONCLUSIONS Among patients undergoing elective CABG, anesthesia with a volatile agent did not result in significantly fewer deaths at 1 year than total intravenous anesthesia. (Funded by the Italian Ministry of Health; MYRIAD ClinicalTrials.gov number, NCT02105610. opens in new tab.) Visual Abstract by Tommaso Scquizzato @ https://twitter.com/tscquizzato #MYRIADtrial #NEJM #CABG #CardiacSurgery #Volatile #Anesthesia

The HYPERION Trial - Targeted Temperature Management for Cardiac Arrest with Nonshockable Rhythm - Visual Abstract NEJM October 2, 2019 - https://www.nejm.org/doi/full/10.1056/NEJMoa1906661 Conclusion: Among patients with coma who had been resuscitated from cardiac arrest with nonshockable rhythm, moderate therapeutic hypothermia at 33°C for 24 hours led to a higher percentage of patients who survived with a favorable neurologic outcome at day 90 than was observed with targeted normothermia. Visual Abstract by Tommaso Scquizzato @ https://twitter.com/tscquizzato #HYPERION #Trial #Hypothermia #CardiacArrest #VisualAbstract #EBM #Nonshockable