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Lab patterns seen in Inborn Errors of Metabolism A table of lab values compiled from UpToDate and Pediatrics In Review, along with my own additions, for diagnosing acute metabolic emergencies. See IEM schema for supplemental information: https://www.grepmed.com/images/5170/metabolicemergency-pathophysiology-differential-pediatrics-metabolism-algorithm-diagnosis #InbornErrors #Metabolism #Neonatology #Peds #Pediatrics #Table #NICU #Genetics #IEM #Laboratory #Patterns #diagnosis
Fluid Resuscitation in Adult Septic Shock - Surviving Sepsis Guidelines 2016 #Management #IVFluid #Resuscitation #SurvivingSepsis #Guidelines #2016
Congestive Heart Failure - Causes, Pathophysiology and Differential Diagnosis • Dilated Cardiomyopathy • Hypertrophic Cardiomyopathy • Restrictive Cardiomyopathy HFrEF Causes: • Cardiovascular • Toxic • Infectious • Other HFpEF Causes: • Afterload • Valvular • Infiltrative • Genetic • Other Dr. Jorge Cortés @Jcortesizaguirr #Congestive #HeartFailure #Causes #Pathophysiology #Differential #Diagnosis #cardiology #HFrEF #HFpEF #CHF
BiPAP titration in CHF - Mean airway pressure provides goodness - Ramp up the ePAP aggressively to achieve high mean airway pressure - Could also use CPAP alone (titrate from 5 cm up to 1 5 cm). BiPAP titration in everything else - Driving pressure supports the work of breathing (equal to iPAP-ePAP). - Ramp up iPAP to increase the driving pressure #BiPAP #Titration #CHF #CongestiveHeartFailure #Management #CriticalCare #Cardiology
Intern Pocket Cards - Inpatient Blood Pressure Management Guide ß-blockers: • Metoprolol, Carvedilol, Labetalol • Bradycardia, heart block, ADHF, COPD exacerbation ACEl/ARBs: • Captopril, Enalaprilat (IV), Lisinopril, Valsartan • AKI, hyperkalemia, angioedema Alpha-2 agonists: • Clonidine • Severe bradycardia Nitrates: • Isosorbide dinitrate • Severe AS, PDE inhibitor use Calcium Channel Blockers (CCBs): • Nifedipine ER, Diltiazem, Amlodipine • HFrEF, For non-dihydropyridines: Bradycardia, heart block Diuretics: • Chlorthalidone, Hydrochlorothiazide, Spironolactone • AKI, hypovolemia, difficulty with transferring to urinate Vasodilators: • Hydralazine • Can develop severe reflex tachycardia due to the unpredictable drop in SBP Non-selective alpha-blockers: • Phentolamine • Can develop severe reflex tachycardia due to the unpredictable drop in SBP Partial D1 agonists • Fenoldopam • Glaucoma Dr. Satya Patel @SatyaPatelMD Full Inpatient Pocket Cards Collection: https://bit.ly/pocketcardset #HTN #hypertension #BloodPressure #medications #Inpatient #pharmacology #table #agents #internship #comparison
Antimicrobial Stewardship De-escalation Algorithm #Antimicrobial #Stewardship #Antibiotics #Deescalation #Algorithm #management
Fluid Stewardship in Septic Shock FOUR PHASES OF FLUID THERAPY Dr. Catherine Beni @totalbodydolor #Fluid #Stewardship #SepticShock #Sepsis #Management #Phases #ROSE #Resus
Misinterpretation of the P-value P-value - Probability for a given statistical model under the null hypothesis (=hypothesis stipulating the equality of 2 statistical parameters) to obtain the same as or of greater magnitude than the actual observed results 1) P-value does not measure the probability of a hypothesis to be true or produced by chance 2) The lower the pretest probability of a hypothesis, the more power is needed to demonstrate the hypothesis 3) P-value implies the statistical significance and does not explain the clinical significance of an effect or result By Dr. Maxime Beydon via Dr. Benjamin Terrier @TerrierBen #PValue #Misinterpretation #biostatistics #diagnosis #pitfalls
Hidden anticholinergics in elderly patients: What, where and how? Antihistamines - 1st generation: chlorpheniramine, hydroxyzine, diphenhydramine Antidepressants - Tricyclic antidepressant: amitriptyline, clomipramine, imipramine - Selective serotonin reuptake inhibitor: Paroxetine Antipsychotics - First generation: chlorpromazine, loxapine - Second generation: clozapine, olanzapine Antiparkinsonians - Benztropine, trihexyphenidyl Antiarrhythmics - Disopyramide Antimuscarinics - Urinary incontinence: oxybutynin, tolterodine - Antispasmodic: atropine, scopolamine Muscle relaxants - Cyclobenzaprine, orphenadrine Antiemetics - Prochlorperazine, promethazine and 1st generation antihistamines By Dr. Sara Thietart @ThietartS via Dr. Benjamin Terrier @TerrierBen #Hidden #anticholinergics #medications #pharmacology #elderly #geriatrics #dementia #diagnosis
Etiologies of pulmonary infections according to CT-scan patterns. CMV cytomegalovirus, GM galactomannan, HSV herpes simplex virus, MDS myelodysplastic syndrome, IF immunofluorescence, PCR polymerase in chain reaction, VZV Varicella–Zoster virus NODULAR LESIONS - Bacterial pneumonia - Aspergillosis - Nocardiosis - Mucormycosis MICRONODULES - Bacterial pneumonia - Viral pneumonia - Mycobacteria GROUND GLASS OPACITIES - Pneumocystosis - Viral pneumonia - Atypical bacterial pneumonia SEPTAL THICKENING - Atypical bacterial pneumonia CAVITATION - Mycobacteria - Histoplasma - Bacterial pneumonia (S. aureus) EXCAVATED NODULES - Bacterial pneumonia - Nocardiosis - Mucormycosis - Actinomyces - Aspergillosis CONSOLIDATION - Bacterial pneumonia - Aspergillosis PLEURAL EFFUSION - Bacterial pneumonia - Tuberculosis https://link.springer.com/epdf/10.1007/s00134-019-05906-5?shared_access_token=FCshMhmvYZdcHlN-0s7lvfe4RwlQNchNByi7wbcMAY4GAssYzjvgnq7IXf0W5aS4XfJyVtXlr2ITA3v4hTmYfMme-weKjqQjyUPzEUtGD7yW0PjtMXCne8_w8-oxtvmJe1RmlxFFJpzgymkqdNRFOw%3D%3D #CT #Patterns #Pulmonary #Lung #Infections #ComputedTomography #Differential #Diagnosis #Chest
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