Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 β€’ Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... Membrane defects (e.g ... #hematology #anemia
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 β€’ Acute infection
 β€’ Solid organ
Causes of Thrombocytosis ... - Differential Diagnosis ... inflammatory disorders (e.g ... #Differential #Diagnosis ... #Causes #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 β€’ Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Willebrand Syndrome - Diagnosis ... Lymphoproliferative disorders (e.g ... Myeloproliferative disorders (e.g ... #Management #treatment ... #hematology #differential
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... (e.g. heparin contamination ... inhibitory drugs (e.g ... specific inhibitor (e.g ... #hematology #coagulation
Raynaud's Syndrome - Washing off under hot water.
Raynaud phenomenon is an exaggerated vasoconstrictive response of the
and arterioles (e.g ... clinical #video #physicalexam ... fingers #hands #rheumatology
β–Ί
Raynaud's Syndrome - Washing off under hot water wath.

Raynaud phenomenon is an exaggerated vasoconstrictive response of
and arterioles (e.g ... clinical #video #physicalexam ... fingers #hands #rheumatology
β–Ί
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 β€’ Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... glucocorticoid treatment ... signs or symptoms (eg ... #Differential #diagnosis ... #hematology #eosinophilia
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or β‰₯ 39 C this is a
Treatment depends ... Surgical devices, e.g ... Sepsis (β†’ 3-14) e.g ... malignant syndrome (e.g ... #Diagnosis #Management
Summary of Coagulation Deficiencies
Inherited:
 β€’ Hemophilia A - Deficiency of Factor VIII
 β€’ Hemophilia B -
Malabsorption (e.g ... warfarin, DOACs (e.g ... Autoimmune disorders (e.g ... table #comparison #diagnosis ... #hematology #deficiency
Mixing Study
 β€’ Clotting tests can be abnormal due to either a clotting factor deficiency, or
factor activity (e.g ... clotting test (e.g ... Mixing #Study #diagnosis ... #hematology #pathophysiology ... #hematology #laboratory