Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief ๐Ÿ‡ต๐Ÿ‡ญ ๐Ÿ‡บ๐Ÿ‡ธ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 โ€ข Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... anemia): ... G6PD deficiency) ... #differential # ... diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 โ€ข Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Diagnosis Algorithm ... #Anemia #Differential ... #workup #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
deficiencies: Iron deficiency ... , G6PD deficiency ... Production #Index #hematology ... #anemia #differential ... #diagnosis #calculation
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 โ€ข Acute infection
 โ€ข Solid organ
malignancies โ€ข Anemia ... specifically: iron deficiency ... , hemolysis, hemorrhage ... #Diagnosis #Causes ... #hematology #secondary
Etiologies of Folate Deficiency
 โ€ข Decreased dietary intake - uncommon in this era
 โ€ข Increased requirements
pregnant have hemolytic ... anemia, or psoriasis ... folate that can cause ... #FolicAcid #differential ... #diagnosis #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
recipients w/ IgA deficiency ... Causes purpura & ... progresses to pancytopenia ... #Transfusions #diagnosis ... #management #hematology
Blood Transfusion Reactions

Immune Mediated:
 โ€ข Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
recipients w/ IgA deficiency ... Causes purpura & ... progresses to pancytopenia ... #Transfusion #diagnosis ... #management #hematology
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isnโ€™t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... an underlying cause ... Better call hematology ... - Some tumors produce ... #workup #hematology