Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Acetaminophen metabolism and factors affecting toxicity. 
GSH = glutathione 

#Acetaminophen #APAP #metabolism #toxicity #Toxicology #Pathophysiology #Overdose
Acetaminophen metabolism ... factors affecting toxicity ... #APAP #metabolism ... #toxicity #Toxicology ... #Pathophysiology
N-Acetyl Cysteine (NAC) Therapy Mechanism of Action: The non-toxic route of APAP metabolism gets saturated in
non-toxic route of APAP ... #Pathophys #Toxicology ... #NAC #APAP #NAcetylCysteine ... #Acetaminophen ... #Toxicity #emDocs
N-Acetylcysteine (NAC) restores hepatic glutathione!
Found to have 21-28% reduction in mortality for acetaminophen-induced hepatic failure
The earlier
concentration of acetaminophen ... ANY overdose of acetaminophen ... ) #Diagnosis #Toxicology ... #Nomogram #Acetaminophen ... #Toxicity #APAP
Fomepizole for Acetaminophen Toxicity

 β€’ In cases where fomepizole and NAC were administered together, evidence has
Fomepizole for Acetaminophen ... Toxicity β€’ ... recommended for massive APAP ... hour equivalent acetaminophen ... #Toxicology #pharmacology