Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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14 results
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... use in cellular metabolism ... Diagnosis of MALA ... LacticAcidosis #Toxicity #Toxicology ... #Diagnosis #Management
Serotonin Syndrome Drug Precipitants and Pharmacology
↑ Serotonin Formation: Tryptophan, Oxitriptan
↑ Serotonin Release: Amphetamines, Cocaine, Mirtazapine
↑ Serotonin
Serotonin Syndrome ... Precipitants and Pharmacology ... Lithium ↓ Serotonin Metabolism ... #Pharmacology # ... #differential #diagnosis
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology ... β†’ Hypokalemia Metabolic ... #Pathophysiology ... #nephrology #diagnosis
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
Propofol infusion syndrome ... Versed) - CYP3A4 metabolism ... No pharmacologic ... (Haldol) - No pharmacologic ... #CriticalCare #diagnosis
Common sodium channel blockers which cause QRS widening.

Anticonvulsants: 
 - Carbamazepine 
Antidysrhythmics:  
 - Group
- Group IA and IC ... widening #ECG #EKG #Pharmacology ... #Medications #Toxicology ... #Diagnosis #Differential
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
Clozapine Toxicology ... - Metabolism - ... #Clozapine #Toxicology ... #Toxicity #Diagnosis ... #Pharmacology
Causes of Seizures - Differential Diagnosis Algorithm
Unprovoked - Epilepsy:
 β€’ Focal: Simple, Complex
 β€’ Generalized: Absence,
- Differential Diagnosis ... Hypertension, ICH ... vasoconstriction syndrome ... Neurocysticercosis, PML β€’ Metabolic ... #Differential #Diagnosis
Propofol-Related Infusion Syndrome (PRIS)

Diagnosis is based on a constellation of clinical suspicion and biochemical signs including:
(PRIS) Diagnosis ... Hyperlactatemia β€’ Metabolic ... #PRIS #Diagnosis ... #Management #Pharmacology ... #Toxicity #Toxicology
Tramadol - Toxicology
Due to different CYP-2D6 genotypes, people variably metabolize tramadol into its active metabolite, M1
This
Tramadol - Toxicology ... people variably metabolize ... #Tramadol #Toxicology ... #Toxicity #Diagnosis ... #Pharmacology
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
and decreased metabolism ... rare): - Reye syndrome ... deficiency #Ammonia #Pathophysiology ... #Differential #Diagnosis