Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief 🇵🇭 🇺🇸 - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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treatment anticoagulation oncology pharmacology cancer cardiology cardiomyopathy chemotherapy cyp3a4 diagnosis inducers inhibitors interactions longterm malignancy perioperative peripartum pglycoprotein preop thromboembolism
Perioperative Management of DOACs Problem: ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
Perioperative Management ... per treatment table ... and procedural bleeding ... with a very low bleeding ... Resumption of Therapy
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓) of cytochrome p450 CYP3A4 and P-glycoprotein. DOACs are substrates
(DOAC interactions ... thereby leading ... metabolization leading ... Chemotherapy #Oncology #Hematology ... #Interactions #Table
Treatment algorithm for VTE in Malignancy (A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
anticoagulant therapy ... DOAC, direct oral ... #DOAC #VTE #Malignancy ... Anticoagulation #Management ... #Hematology #Oncology
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
Avoid Warfarin and DOAC ... Delivery • Stable ... Period • Breast-feeding ... deteriorating on medical therapy ... investigative therapy
Longterm Venous Thromboembolism Treatment Algorithm Treat for 3 months and reassess • Isolated distal DVT (without cancer)
Thromboembolism Treatment Algorithm ... PE - High Bleeding ... - Not High Bleeding ... Thromboembolism #Treatment #Algorithm ... #management #hematology
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