Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Differential diagnosis of Langerhans cell histiocytosis.
Nodular LCH:
- Sarcoidosis: perilymphatic distribution.
- Metastases: random distribution.
Cystic LCH:
- LAM: round
Langerhans cell histiocytosis ... Clinical #Diagnosis #Radiology ... #Cysts #Differential ... #Comparison #Table ... #RadiologyAssistant
On the left three different patients with lung cysts.
From left to right: Lymphangiomyomatosis, LIP and Langerhans
patients with lung cysts ... Langerhans cell histiocytosis ... Clinical #Diagnosis #Radiology ... #CTChest #Cystic ... #RadiologyAssistant
Low Attenuation pattern (2) 
1. Centrilobular emphysema: low attenuation areas without walls. Notice the centrilobular artery
Langerhans cell histiocytosis ... (LAM): regular cysts ... #Clinical #Radiology ... Pattern #Comparison #Table ... #RadiologyAssistant
The fourth pattern includes abnormalities that result in decreased lung attenuation or air-filled lesions.
These include:
- Emphysema
-
Emphysema - Lung cysts ... Langerhans cell histiocytosis ... #Diagnosis #Radiology ... LowAttenuation #Differential ... Emphysema #SignetRing #RadiologyAssistant
Upper lung zone preference is seen in:
- Inhaled particles: pneumoconiosis (silica or coal)
- Smoking related diseases
Langerhans cell histiocytosis ... edema #Diagnosis #Radiology ... HRCT #ChestCT #Differential ... #Table #Distribution ... #Upper #Lower #RadiologyAssistant
Nodular pattern(2)
1. Sarcoidosis: nodules with perilymphatic distribution, along fissures, adenopathy.
2. TB: Tree-in-bud appearance in a patient
Langerhans cell histiocytosis ... before the typical cysts ... #Clinical #Radiology ... Pattern #Comparison #Table ... #RadiologyAssistant
Low Attenuation pattern 
1. Lymphangiomyomatosis (LAM): uniform cysts in woman of child-bearing age; no history of
(LAM): uniform cysts ... bizarre shaped cysts ... #Clinical #Radiology ... Pattern #Comparison #Table ... #RadiologyAssistant
Differential diagnosis on HRCT
Most of our knowledge about imaging findings in interstitial lung disease comes from
Differential diagnosis ... low attenuation (table ... Langerhans cell histiocytosis ... #Diagnosis #Radiology ... #RadiologyAssistant
On the left some diseases with a nodular pattern.
1. Hypersensitivity pneumonitis: ill defined centrilobular nodules.
2. Miliary
Langerhans cell histiocytosis ... before the typical cysts ... NodularPattern #Differential ... #Comparison #Table ... #RadiologyAssistant
Multiple masses
The differential diagnostic list of multiple masses is very long.
The most important diagnoses are listed
Multiple masses The differential ... listed in the table ... is difficult to differentiate ... #Management #Radiology ... #RadiologyAssistant