Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Differential diagnosis of Langerhans cell histiocytosis.
Nodular LCH:
- Sarcoidosis: perilymphatic distribution.
- Metastases: random distribution.
Cystic LCH:
- LAM: round
Langerhans cell histiocytosis ... #Diagnosis #Radiology ... #Cysts #Differential ... #Comparison #Table ... #RadiologyAssistant
Low Attenuation pattern (2) 
1. Centrilobular emphysema: low attenuation areas without walls. Notice the centrilobular artery
Langerhans cell histiocytosis ... (LAM): regular cysts ... #Clinical #Radiology ... Pattern #Comparison #Table ... #RadiologyAssistant
Upper lung zone preference is seen in:
- Inhaled particles: pneumoconiosis (silica or coal)
- Smoking related diseases
bronchiolitis (RB-ILD ... Langerhans cell histiocytosis ... edema #Diagnosis #Radiology ... HRCT #ChestCT #Differential ... #Table #Distribution
On the left some diseases with a nodular pattern.
1. Hypersensitivity pneumonitis: ill defined centrilobular nodules.
2. Miliary
before the typical cysts ... #Clinical #Diagnosis ... #Radiology #Pulmonary ... #Comparison #Table ... #RadiologyAssistant
Nodular pattern(2)
1. Sarcoidosis: nodules with perilymphatic distribution, along fissures, adenopathy.
2. TB: Tree-in-bud appearance in a patient
Langerhans cell histiocytosis ... before the typical cysts ... #Clinical #Radiology ... Pattern #Comparison #Table ... #RadiologyAssistant
Cavities frequently arise within a mass or an area of consolidation as a result of necrosis.
We
Langerhans cell histiocytosis ... with end-stage fibrosis ... #Clinical #Diagnosis ... #Radiology #CTChest ... Emphysema #Comparison #RadiologyAssistant
Differential diagnosis on HRCT
Most of our knowledge about imaging findings in interstitial lung disease comes from
Differential diagnosis ... low attenuation (table ... Langerhans cell histiocytosis ... #Diagnosis #Radiology ... #RadiologyAssistant
HRCT findings in UIP
Honeycombing consisting of multilayered thick-walled cysts.
Architectural distortion with traction bronchiectasis due to fibrosis.
Predominance
multilayered thick-walled cysts ... lymphadenopathy #Clinical ... #Radiology #CTChest ... #Pneumonitis #ILD ... #RadiologyAssistant
On the left a chest film of a 19 year old patient with Langerhans cell histiocytosis.
The
film of a 19 year old ... caused by multiple cysts ... most challenging differential ... #Clinical #Radiology ... #Cystic #RadiologyAssistant
Differential diagnosis of Lymphangiomyomatosis:
Langerhans cell histiocytosis: > 90% are smokers, cysts have irregular shapes and the
Differential diagnosis ... Langerhans cell histiocytosis ... 90% are smokers, cysts ... #Clinical #Radiology ... #RadiologyAssistant