Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Differential diagnosis of Langerhans cell histiocytosis.
Nodular LCH:
- Sarcoidosis: perilymphatic distribution.
- Metastases: random distribution.
Cystic LCH:
- LAM: round
Langerhans cell histiocytosis ... Nodular LCH: - Sarcoidosis ... #Cysts #Differential ... #Comparison #Table ... #RadiologyAssistant
On the left some diseases with a nodular pattern.
1. Hypersensitivity pneumonitis: ill defined centrilobular nodules.
2. Miliary
before the typical cysts ... #Clinical #Diagnosis ... #Radiology #Pulmonary ... #Comparison #Table ... #RadiologyAssistant
Nodular pattern(2)
1. Sarcoidosis: nodules with perilymphatic distribution, along fissures, adenopathy.
2. TB: Tree-in-bud appearance in a patient
Langerhans cell histiocytosis ... before the typical cysts ... #Clinical #Radiology ... Pattern #Comparison #Table ... #RadiologyAssistant
Low Attenuation pattern (2) 
1. Centrilobular emphysema: low attenuation areas without walls. Notice the centrilobular artery
Langerhans cell histiocytosis ... (LAM): regular cysts ... #Clinical #Radiology ... Pattern #Comparison #Table ... #RadiologyAssistant
Upper lung zone preference is seen in:
- Inhaled particles: pneumoconiosis (silica or coal)
- Smoking related diseases
bronchiolitis (RB-ILD ... Langerhans cell histiocytosis ... edema #Diagnosis #Radiology ... HRCT #ChestCT #Differential ... #Table #Distribution
Nodular pattern
1. Hypersensitivity pneumonitis: ill defined centrilobular nodules.
2. Miliary TB: random nodules
3. Sarcoidosis: nodules with perilymphatic
Nodular pattern ... Hypersensitivity pneumonitis: ill ... #Clinical #Radiology ... Pattern #Comparison #Table ... #RadiologyAssistant
On the left another case of Langerhans' cell histiocytosis.
It started as small noduli, which progressed over
started as small noduli ... to cavitating nodules ... bizarre shaped cysts ... #Clinical #Radiology ... #Cystic #RadiologyAssistant
HRCT findings in Langerhans cell histiocytosis:
Early stage:
- Small irregular or stellate nodules in centrilobular location.
Late stage
irregular or stellate nodules ... airspaces Cysts ... with small nodules ... #Clinical #Radiology ... #RadiologyAssistant
Differential diagnosis on HRCT
Most of our knowledge about imaging findings in interstitial lung disease comes from
patterns: reticular, nodular ... low attenuation (table ... Langerhans cell histiocytosis ... #Diagnosis #Radiology ... #RadiologyAssistant
Cavities frequently arise within a mass or an area of consolidation as a result of necrosis.
We
In the differential ... Langerhans cell histiocytosis ... #Clinical #Diagnosis ... #Radiology #CTChest ... Emphysema #Comparison #RadiologyAssistant