Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Differential diagnosis of Langerhans cell histiocytosis.
Nodular LCH:
- Sarcoidosis: perilymphatic distribution.
- Metastases: random distribution.
Cystic LCH:
- LAM: round
Langerhans cell histiocytosis ... Nodular LCH: - Sarcoidosis ... #Cysts #Differential ... #Comparison #Table ... #RadiologyAssistant
Nodular pattern(2)
1. Sarcoidosis: nodules with perilymphatic distribution, along fissures, adenopathy.
2. TB: Tree-in-bud appearance in a patient
Langerhans cell histiocytosis ... before the typical cysts ... #Clinical #Radiology ... Pattern #Comparison #Table ... #RadiologyAssistant
On the left some diseases with a nodular pattern.
1. Hypersensitivity pneumonitis: ill defined centrilobular nodules.
2. Miliary
Langerhans cell histiocytosis ... before the typical cysts ... NodularPattern #Differential ... #Comparison #Table ... #RadiologyAssistant
Liver Mass Differential Diagnosis
Solid:
 β€’ Benign: Hepatic Hemangioma, Focal nodular hyperplasia, Hepatocellular adenoma, Regenerative nodules
 β€’
Liver Mass Differential ... Hemangioma, Focal nodular ... , Regenerative nodules ... #Diagnosis #hepatology ... #Radiology
Low Attenuation pattern (2) 
1. Centrilobular emphysema: low attenuation areas without walls. Notice the centrilobular artery
Langerhans cell histiocytosis ... (LAM): regular cysts ... #Clinical #Radiology ... Pattern #Comparison #Table ... #RadiologyAssistant
On the left another case of Langerhans' cell histiocytosis.
It started as small noduli, which progressed over
started as small noduli ... to cavitating nodules ... bizarre shaped cysts ... #Clinical #Radiology ... #Cystic #RadiologyAssistant
The fourth pattern includes abnormalities that result in decreased lung attenuation or air-filled lesions.
These include:
- Emphysema
-
Emphysema - Lung cysts ... Langerhans cell histiocytosis ... #Diagnosis #Radiology ... LowAttenuation #Differential ... Emphysema #SignetRing #RadiologyAssistant
Upper lung zone preference is seen in:
- Inhaled particles: pneumoconiosis (silica or coal)
- Smoking related diseases
Langerhans cell histiocytosis ... edema #Diagnosis #Radiology ... HRCT #ChestCT #Differential ... #Table #Distribution ... #Upper #Lower #RadiologyAssistant
Differential diagnosis on HRCT
Most of our knowledge about imaging findings in interstitial lung disease comes from
patterns: reticular, nodular ... low attenuation (table ... Langerhans cell histiocytosis ... #Diagnosis #Radiology ... #RadiologyAssistant
HRCT findings in Langerhans cell histiocytosis:
Early stage:
- Small irregular or stellate nodules in centrilobular location.
Late stage
irregular or stellate nodules ... airspaces Cysts ... with small nodules ... #Clinical #Radiology ... #RadiologyAssistant