Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Antiphospholipid Syndrome (APS)
APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid Syndrome ... to be present Treatment ... Guidelines): β€’ Anticoagulation ... Antiphospholipid #Syndrome ... #management #anticoagulation
Low-dose aspirin and low-molecular-weight heparin in lupus and Antiphospholipid Syndrome (APS) pregnancy

β€’ No previous history of
Antiphospholipid Syndrome ... gestation : Aspirin + preventive ... : Aspirin Β± preventive ... Antiphospholipid #Syndrome ... #Obstetrics #Anticoagulation
Behcet's Syndrome - Treatment
Ulcers:
 β€’ Treatment: Topical steroids
 β€’ Prevention: Colchicine
 β€’ Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... Topical steroids β€’ Prevention ... immunosuppressive meds β€’ +/- Anticoagulation ... Behcets #disease #Syndrome ... #pharmacology #rheumatology
2019 EULAR recommendations for thrombosis in (Antiphospholipid Syndrome) APS
Venous Thrombosis - Arterial Thrombosis
INR Target
Duration
Recurrence

Dr. Laurent ARNAUD
Antiphospholipid Syndrome ... ) APS Venous Thrombosis ... Antiphospholipid #Syndrome ... #APS #management ... #hematology #treatment
2019 EULAR Recommendations - Obstetrics Management in (Antiphospholipid Syndrome) APS
Previous Thrombosis?
Previous Pregnancy Complications?

Dr. Laurent ARNAUD @Lupusreference

#obstetrics
Antiphospholipid Syndrome ... ) APS Previous ... #APS #management ... EULAR2019 #guidelines #rheumatology ... #obgyn #treatment
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 β€’ Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
: - Neuro: AMS ... have fever - ACS ... organ damage β€’ Treatment ... Low calcium β€’ Treatment ... diagnosis #management #hematology
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Disease - Capillary leak ... syndrome Epidemiology ... disease flares: β€’ Prevention ... Disease #Capillary #leak ... #rheumatology
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
Treatment algorithm ... (A) Suggested treatment ... initiated after a LMWH lead-in ... Cancer #Algorithm #Anticoagulation ... #Management #Hematology
Fever vs Hyperthermia
Fever:
 β€’ Regulated in the hypothalamic thermoregulatory center
 β€’ "Set point" raised by prostaglandin
Neuroleptic malignant syndrome ... ; Serotonin syndrome ... can cause harm as ... they lead to peripheral ... vasoconstriction, preventing
Clotmaster Consensus 2019: Duration of Therapy for Venous Thromboembolic Disease
 β€’ Superficial Venous Thrombosis
 β€’ Upper
DVT or PE - Prevention ... post-thrombotic syndrome ... Bloodman #VTE #anticoagulation ... management #DVT #hematology ... #length #treatment