Mithu Maheswaranathan, MD @MithuRheum
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Rheumatologist at Duke University Creator of Rheum OnePagers ➡ RheumOnePagers.com Twitter: @MithuRheum ➡ https://twitter.com/MithuRheum
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diagnosis rheumatology antibodies ana antinuclear differential associations autoantibodies clinical myositis specific
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... (SSc) • Nucleolar ... systemic sclerosis/scleroderma ... systemic sclerosis/scleroderma ... Antibodies #ANA #patterns
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
serial dilution, a pattern ... significant • Pattern ... : The ANA patterns ... not specific ANA Patterns ... (SSc) • Nucleolar
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Anti-JO-1, Others: SRP ... TIF1y, MDA5 • Scleroderma ... Systemic Sclerosis, SSc ... #associations #table
Myositis Specific Antibodies (MSAs) Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ Immune Mediated
Specific Antibodies (MSAs ... (IMNM): HMGCR, SRP ... Specific #Antibodies #MSAs ... #rheumatology #table
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