Mithu Maheswaranathan, MD @MithuRheum
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Rheumatologist at Duke University Creator of Rheum OnePagers ➡ RheumOnePagers.com Twitter: @MithuRheum ➡ https://twitter.com/MithuRheum
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Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
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Systemic Sclerosis (Scleroderma ... (SSc): • Limited ... renal crisis (SRC ... #SSc #rheumatology ... signs #symptoms #testing
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
) and Anti-La (SSB ... Anti-JO-1, Others: SRP ... TIF1y, MDA5 • Scleroderma ... Systemic Sclerosis, SSc ... #associations #table
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Sjogren's Syndrome (SS ... (SSc) • Nucleolar ... systemic sclerosis/scleroderma ... Antibodies #ANA #patterns
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
: The ANA patterns ... but often not specific ... ANA Patterns and ... Sjogren's Syndrome (SS ... (SSc) • Nucleolar