Mithu Maheswaranathan, MD @MithuRheum
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Rheumatologist at Duke University Creator of Rheum OnePagers ➡ RheumOnePagers.com Twitter: @MithuRheum ➡ https://twitter.com/MithuRheum
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ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... or scleroderma ... (SSc) • Nucleolar ... /scleroderma • ... Antibodies #ANA #patterns
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Systemic Sclerosis ... (Scleroderma) ... (SSc): • Limited ... renal crisis (SRC ... #Scleroderma #SSc
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
: The ANA patterns ... or scleroderma ... (SSc) • Nucleolar ... /scleroderma • ... (scleroderma),
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Anti-JO-1, Others: SRP ... TIF1y, MDA5 • Scleroderma ... (Systemic Sclerosis ... , SSc): Anti-centromere ... #associations #table