Mithu Maheswaranathan, MD @MithuRheum
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Rheumatologist at Duke University Creator of Rheum OnePagers ➡ RheumOnePagers.com Twitter: @MithuRheum ➡ https://twitter.com/MithuRheum
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ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... (SSc) • Nucleolar ... systemic sclerosis/scleroderma ... systemic sclerosis/scleroderma ... Antibodies #ANA #patterns
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
serial dilution, a pattern ... significant • Pattern ... : The ANA patterns ... not specific ANA Patterns ... (SSc) • Nucleolar
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Anti-JO-1, Others: SRP ... TIF1y, MDA5 • Scleroderma ... Systemic Sclerosis, SSc ... #associations #table
Scleroderma Renal Crisis (SRC)

Clinical Presentation of Scleroderma Renal Crisis:
1) Acute kidney injury
2) Abrupt onset of hypertension
3)
Scleroderma Renal ... Crisis (SRC) ... of arteries Management ... MithuRheum #SRC ... nephrology #diagnosis #management