The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Alzheimer’s Disease ... Alzheimer's (99% of cases ... chromosome 21) Signs / Symptoms ... pathophysiology #geriatrics #diagnosis ... #signs #symptoms
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
findings - For diagnosis ... to 25 for new diagnosis ... their turn • Causes ... Pathophysiology #diagnosis ... #psychiatry #criteria
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
• Other rare causes ... Cardiovascular disease ... Overproduction #diagnosis ... #signs #symptoms
Bulimia Nervosa: Signs and Symptoms
Associated Psychological / Behavioural Features
 • Feelings of shame, guilt and embarrassment
Nervosa: Signs and Symptoms ... erosion and gum disease ... Sores, scars, calluses ... inducing vomiting #BulimiaNervosa ... pathophysiology #diagnosis
Kawasaki Disease: Clinical Findings
Diagnostic Criteria - Fever and 4/5 of the following:
 • Conjunctivitis
 • Polymorphous
Kawasaki Disease ... Clinical Findings Diagnostic ... Criteria - Fever ... feet Signs/Symptoms ... #Criteria #Diagnosis
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
inflammation tends to cause ... interstitial lung disease ... pathophysiology #signs #symptoms ... #diagnosis #ExtraArticular
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
• Inflammatory Disease ... • Hematologic Disease ... retinal edema caused ... ophthalmology #diagnosis ... #signs #symptoms
Mixed Urinary Incontinence: Pathogenesis and Clinical Findings

Urgency Urinary Incontinence (UUI) -> Urinary leakage preceded by a
SUI or UUI not caused ... Pathophysiology #Signs #Symptoms ... #Urology #Diagnosis
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
epidemiology of this disease ... 40% of patients diagnosed ... history of the disease ... to produce all classes ... immunity Signs/Symptoms
Varicocele: Pathogenesis and clinical findings
Primary:
 - Anatomically: the left spermatic vein drains into the left renal
retroperitoneal masses ... Pathophysiology #Signs #Symptoms ... #Urology #Diagnosis