The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Hypersensitivity: Summary Type ... conjunctivitis Type ... Stevens-Johnson Syndrome ... #Types #Classification ... #Diagnosis #Definitions
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
Type IV Hypersensitivity ... causes development ... Allergic reaction ... Stevens-Johnson Syndrome ... ivy) #TypeIV #Type4
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
Definitions • Type ... cell surfaces causes ... causes development ... #Types #Classification ... #Diagnosis #Definitions
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
• Serotonin Syndrome ... SSRI Withdrawal Syndrome ... Dizziness - Nausea ... #SideEffects #Psychiatry ... #Diagnosis #Signs
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Diarrhea, Insomnia, Nausea ... Vomiting Serotonin Syndrome ... gain Incr NE: Nausea ... #SideEffects #Psychiatry ... #Diagnosis #Signs
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
constipation • Allergic ... Stevens-Johnson Syndrome ... Systemic effect -> Nausea ... Pathophysiology #Psychiatry
Mental Status Exam (MSE)
Note: The MSE is a "snapshot" of a patient at a specific time.
You
(Type, Range, Appropriate ... Thought Content - Types ... , the symptoms caused ... MentalStatusExam #MSE #psychiatry ... #diagnosis #evaluation
Serotonin Syndrome: Pathogenesis and Clinical Findings
Serotonin Syndrome: Variable combination of mental status changes, autonomic instability, and
Serotonin Syndrome ... ingestion and most cases ... make a clinical diagnosis ... Pathophysiology #Psychiatry ... #Diagnosis #Signs
Bulimia Nervosa: Complications
GASTROINTESTINAL
 • Dehydration & inability to digest food -> Constipation
 • Recurrent vomiting exposes
• Boerhaave syndrome ... hormone levels cause ... pathophysiology #diagnosis ... signs #symptoms #psychiatry