The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology sideeffects signs symptoms allergic allergy definitions hypersensitivity inhibitors serotonin types anticonvulsants antipsychotics bulimianervosa complications firstgeneration mechanism mechanisms moodstabilizers serotoninnorepinephrine
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect Examples: Valproate, Carbamazepine, Lamotrigine • Mild anticholinergic effect -> Drowsiness
mediated cytotoxic reaction ... Stevens-Johnson Syndrome ... Systemic effect -> Nausea ... Pathophysiology #Psychiatry ... #Pharmacology
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects • Serotonin Syndrome: - Autonomic Hyperactivity:
• Serotonin Syndrome ... Dizziness - Nausea ... Pathophysiology #Pharmacology ... #SideEffects #Psychiatry ... #Diagnosis #Signs
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Stevens-Johnson Syndrome ... Dermatitis (ie. reaction ... Allergy #Allergic #Reactions ... #Types #Classification ... #Diagnosis #Definitions
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting Serotonin Syndrome - Potentially Life
Vomiting Serotonin Syndrome ... gain Incr NE: Nausea ... Pathophysiology #Pharmacology ... #SideEffects #Psychiatry ... #Diagnosis #Signs
Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
cell surfaces causes ... an immune reaction ... exposure to allergen causes ... #Types #Classification ... #Diagnosis #Definitions
First Generation Anti-Psychotics: Mechanisms and Side Effects Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine ACh M1 antagonist - Block
, and/or limbs caused ... #SideEffects #pharmacology ... #diagnosis #psychiatry
Serotonin Syndrome: Pathogenesis and Clinical Findings Serotonin Syndrome: Variable combination of mental status changes, autonomic instability, and
Serotonin Syndrome ... ingestion and most cases ... make a clinical diagnosis ... Pathophysiology #Psychiatry ... #Diagnosis #Signs
Bulimia Nervosa: Complications GASTROINTESTINAL • Dehydration & inability to digest food -> Constipation • Recurrent vomiting exposes
• Boerhaave syndrome ... hormone levels cause ... pathophysiology #diagnosis ... signs #symptoms #psychiatry
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