The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology diagnosis gh growthhormone pituitary signs symptoms 21ohd criteria feedbackloop genetics glftap hyperthyroidism macroadenoma masseffects narcissistic npd overproduction pediatrics peds
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
Growth Hormone Excess ... of onset of GH excess ... GH excess prior ... GH excess after ... signs #symptoms #endocrinology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
thyrotoxicosis due to excess ... hyperthyroidism due to excess ... Hyperthyroidism #endocrinology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
a scrotum #21HydroxylaseDeficiency ... pathophysiology #genetics #endocrinology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
lipid • GH excess ... #FeedbackLoop #endocrinology
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
A good mnemonic ... #SideEffects #endocrinology ... #mnemonic #GLFTAP
Narcissistic Personality Disorder: Pathogenesis and Clinical Findings • Arrogant, Haughty Behaviors or Attitude - Often display
of others NPD Mnemonic ... - Entitlement, Excess ... Signs #Symptoms #Mnemonic
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