The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Diabetic Nephropathy: Pathogenesis
 - Metabolic Pathway
 - Hemodynamic Pathway

#Diabetic #Nephropathy #Diabetes #pathophysiology
Diabetic Nephropathy ... Hemodynamic Pathway #Diabetic ... #Nephropathy #Diabetes
Erectile Dysfunction: Pathogenesis

Erectile Dysfunction - Persistent or recurrent inability to achieve an erection sufficient to achieve
trauma, iatrogenic, diabetes ... and rigidity Endocrinologic ... hyperlipidemia, diabetes ... (penile artery diameter
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
Diabetic Ketoacidosis ... pathophysiology #endocrinology ... #diabetes
Diabetic Retinopathy: Pathogenesis and clinical findings

Mild Non-proliferative DR
 • Outpouchings of the weakened capillary walls or
Diabetic Retinopathy ... Neovascularization #Diabetic ... #Retinopathy #Diabetes
Diabetic Foot: Pathogenesis and clinical findings
 • Polyol Pathway - Excess glucose enters Polyol pathway ->
Diabetic Foot: Pathogenesis ... neuropathy => Diabetic ... a person with diabetes ... complications #Diabetes
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
Hyperprolactinemia • Diabetes ... #SideEffects #endocrinology
Spondylosis - Pathogenesis and Complications

Vertebral disease that may compress the vertebral canal from all sides
Note: Do
pathophysiology #msk
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
pathophysiology #endocin #endocrinology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings

Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Hyperthyroidism #endocrinology
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
StressFractures #msk