The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology diagnosis genetics pediatrics peds 21hydroxylasedeficiency 21ohd alzheimersdisease complications constipation dementia diabeticfoot diabeticketoacidosis dka erectile fecal glftap incontinence macroadenoma masseffects
Erectile Dysfunction: Pathogenesis Erectile Dysfunction - Persistent or recurrent inability to achieve an erection sufficient to achieve
Erectile Dysfunction ... trauma, iatrogenic, diabetes ... and rigidity Endocrinologic ... hyperlipidemia, diabetes ... (penile artery diameter
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
Executive planning dysfunction ... concentration • Motor dysfunction ... pathophysiology #geriatrics
Diabetic Foot: Pathogenesis and clinical findings • Polyol Pathway - Excess glucose enters Polyol pathway ->
Diabetic Foot: Pathogenesis ... increasing cytogenetic dysfunction ... neuropathy => Diabetic ... a person with diabetes ... complications #Diabetes
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
Hyperprolactinemia • Diabetes ... • Hypothalamic dysfunction ... #SideEffects #endocrinology
Fecal Incontinence - Pathogenesis and Complications Continence mechanisms are impaired • Local neuronal damage • External and
Diabetes) • Altered ... #Incontinence #geriatrics
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
Diabetic Ketoacidosis ... pathophysiology #endocrinology ... #diabetes
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Obesity -> Type 2 diabetes ... pathophysiology #peds #pediatrics
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
pathophysiology #genetics #endocrinology ... #peds #pediatrics
Pathogenesis of Select Causes of Constipation in Adults and in Elderly • Mechanical (ex. Bowel Obstruction,
CNS neurons -> Dysfunction ... pathophysiology #geriatrics
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