The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology diagnosis signs symptoms diabetes 21hydroxylasedeficiency 21ohd alzheimersdisease caudaequina dementia diabeticfoot diabeticketoacidosis dka genetics geriatrics glftap macroadenoma masseffects mnemonic msk
Erectile Dysfunction: Pathogenesis Erectile Dysfunction - Persistent or recurrent inability to achieve an erection sufficient to achieve
Erectile Dysfunction ... Dysfunction - Persistent ... Dysfunction Sudden ... and rigidity Endocrinologic ... Erectile Dysfunction
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
Signs / Symptoms / Complications ... Executive planning dysfunction ... concentration • Motor dysfunction
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
Signs / Symptoms / Complications ... • Hypothalamic dysfunction ... #SideEffects #endocrinology
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Signs / Symptoms / Complications ... bladder/bowel dysfunction
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Signs/Symptoms/Complications ... pathophysiology #genetics #endocrinology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
Signs/Symptoms/Complications ... pathophysiology #endocrinology
Diabetic Foot: Pathogenesis and clinical findings • Polyol Pathway - Excess glucose enters Polyol pathway ->
increasing cytogenetic dysfunction ... pathophysiology #complications
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: Complications ... causes middle ear dysfunction ... signs #symptoms #complications
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