The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology growthhormone pituitary diagnosis glftap hyperthyroidism macroadenoma masseffects overproduction sideeffects
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... /Symptoms: • GH ... excess: - ... #FeedbackLoop # ... endocrinology #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
time of onset of GH ... GH excess prior ... GH excess after ... #diagnosis #signs ... #symptoms #endocrinology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Primary Hyperthyroidism ... thyrotoxicosis due to excess ... hyperthyroidism due to excess ... Signs/Symptoms: ... Hyperthyroidism #endocrinology
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
following order; GH ... A good mnemonic ... Signs / Symptoms ... #SideEffects #endocrinology ... #mnemonic #GLFTAP
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