The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology diagnosis signs symptoms acute alzheimersdisease caudaequina dementia excess geriatrics glftap growthhormone injury macroadenoma masseffects mnemonic neurology orthopedics overproduction pagetsdisease
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
time of onset of GH ... GH excess prior ... GH excess after ... Carpal Tunnel Syndrome ... signs #symptoms #endocrinology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Anterior Cord Syndrome ... • Central Cord Syndrome ... Upper Extremity Dysfunction ... deficiencies -> Sphincter dysfunction ... signs #symptoms #msk
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
following order; GH ... Signs / Symptoms / Complications ... • Hypothalamic dysfunction ... #SideEffects #endocrinology
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Cauda Equina Syndrome ... Signs / Symptoms / Complications ... bladder/bowel dysfunction ... #CaudaEquina #Syndrome ... #MSK #pathophysiology
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
mutations - Down syndrome ... Signs / Symptoms / Complications ... Executive planning dysfunction ... concentration • Motor dysfunction
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: Complications ... bone formation MSK ... causes middle ear dysfunction ... signs #symptoms #complications
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