The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Menstrual Cycle Physiology: Ovarian Cycle – Brief Overview
LH and FSH are required for follicular development and
not implant #MenstrualCycle ... #OvarianCycle #pathophysiology ... #menstruation #endocrinology
Menstrual Cycle Physiology: The Hypothalamic-Pituitary-Ovarian Axis
Estrogen, when released:
 • Negatively feeds back on the hypothalamus and
#MenstrualCycle ... #pathophysiology ... HypothalamicPituitary #endocrinology
Menstrual Cycle Physiology: Ovarian Cycle – Ovulation Explained

Around Day 14, estrogen exerts sudden +++ positive feedback
for clarity) #MenstrualCycle ... #OvarianCycle #pathophysiology ... #Ovulation #endocrinology
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Signs / Symptoms / Complications ... Executive planning dysfunction ... concentration • Motor dysfunction ... AlzheimersDisease #Dementia #pathophysiology
Erectile Dysfunction: Pathogenesis

Erectile Dysfunction - Persistent or recurrent inability to achieve an erection sufficient to achieve
Erectile Dysfunction ... Pathogenesis Erectile Dysfunction ... and rigidity Endocrinologic ... Erectile Dysfunction ... #Pathophysiology
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
Signs / Symptoms / Complications ... • Hypothalamic dysfunction ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Menstrual Cycle Physiology: Ovarian Cycle – Luteal Phase Explained
 • The LH surge can be thought
Ovarian Cycle #MenstrualCycle ... #OvarianCycle #pathophysiology ... #LutealPhase #endocrinology
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Signs / Symptoms / Complications ... bladder/bowel dysfunction ... Syndrome #MSK #pathophysiology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology