The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Menstrual Cycle Physiology: Ovarian Cycle – Ovulation Explained

Around Day 14, estrogen exerts sudden +++ positive feedback
Ovarian Cycle – Ovulation ... sudden +++ positive feedback ... negative to positive feedback ... MenstrualCycle #OvarianCycle ... #endocrinology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Feedback Loop: Growth ... activates lipolysis Signs ... metabolic abn #GrowthHormone ... #FeedbackLoop #endocrinology
Menstrual Cycle Physiology: Ovarian Cycle – Brief Overview
LH and FSH are required for follicular development and
continued growth until ovulation ... theca cells • Ovulation ... forms following ovulation ... MenstrualCycle #OvarianCycle ... #menstruation #endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
fraction • HTN #GrowthHormone ... Overproduction #diagnosis #signs ... #symptoms #endocrinology
Menstrual Cycle Physiology: Correlating the Ovarian and Uterine Cycles
Note: Some charts show different relative levels of
Ovulation • ... See also "Ovulation ... • After ovulation ... MenstrualCycle #OvarianCycle ... pathophysiology #comparison #endocrinology
Menstrual Cycle Physiology: Ovarian Cycle – Luteal Phase Explained
 • The LH surge can be thought
slide) Besides ovulation ... MenstrualCycle #OvarianCycle ... #LutealPhase #endocrinology
Menstrual Cycle Physiology: Ovarian Cycle – Follicular Phase Explained
Early Follicular Phase (Days 0-5)
 • Granulosa cells
preparing for ovulation ... MenstrualCycle #OvarianCycle ... FollicularPhase #endocrinology