The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Menstrual Cycle Physiology: Ovarian Cycle – Brief Overview
LH and FSH are required for follicular development and
MenstrualCycle #OvarianCycle ... #pathophysiology ... #menstruation #endocrinology
Menstrual Cycle Physiology: Ovarian Cycle – Ovulation Explained

Around Day 14, estrogen exerts sudden +++ positive feedback
MenstrualCycle #OvarianCycle ... #pathophysiology ... #Ovulation #endocrinology
Distinguishing between Inflammatory and Degenerative joint disease
Inflammatory Joint Disease
 • Swelling stimulates joint nociceptors -> Pain
Inflammatory and Degenerative ... ESR, RF, ANA) Degenerative ... #Comparison #Versus ... #MSK #JointDisease ... JointPain #Diagnosis #pathophysiology
Disc Herniations - Pathogenesis and Complications
• 90% of Lumbar disc herniations happen at L4/5 and L5/S1
•
C6/7 Aging ->Degeneration ... complications #msk ... #pathophysiology
Menstrual Cycle Physiology: Correlating the Ovarian and Uterine Cycles
Note: Some charts show different relative levels of
follicle (others degenerate ... MenstrualCycle #OvarianCycle ... #pathophysiology ... #comparison #endocrinology
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
• Large lumbar degenerative ... CaudaEquina #Syndrome #MSK ... #pathophysiology
Menstrual Cycle Physiology: Ovarian Cycle – Luteal Phase Explained
 • The LH surge can be thought
MenstrualCycle #OvarianCycle ... #pathophysiology ... #LutealPhase #endocrinology
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
around the hip • Degeneration ... Trendelenburg #Gait #pathophysiology ... signs #diagnosis #msk
Menstrual Cycle Physiology: Ovarian Cycle – Follicular Phase Explained
Early Follicular Phase (Days 0-5)
 • Granulosa cells
MenstrualCycle #OvarianCycle ... #pathophysiology ... FollicularPhase #endocrinology
Menstrual Cycle Physiology: the Uterine Cycle
The endometrium has receptors for ovarian hormones! Changes in structure and
MenstrualCycle #OvarianCycle ... #pathophysiology ... #UterineCycle #endocrinology