The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis symptoms gh cubitaltunnel excess feedbackloop keratoconus msk overproduction periorbital pituitary retinoblastoma
Orbital Cellulitis: Pathogenesis and Clinical Findings Definitions: a. Chemosis: Edema of the bulbar conjunctiva b. Panopthalmitis: inflammation of all
Orbital Cellulitis ... anterior to the orbital ... #Cellulitis #pathophysiology ... #ophthalmology ... #diagnosis #signs
Cubital Tunnel Syndrome: Pathogenesis and clinical findings • Paresthesia of 5th and medial half of 4th
Cubital Tunnel Syndrome ... over cubital tunnel ... CubitalTunnel #Syndrome ... #Diagnosis #pathophysiology ... #signs #symptoms
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
Carpal Tunnel Syndrome ... fraction • HTN #GrowthHormone ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... metabolic abn #GrowthHormone ... #FeedbackLoop #endocrinology ... #pathophysiology
Periorbital Cellulitis: Pathogenesis and Clinical Findings Definitions: a. Dacryoadenitis: infection of the lacrimal glands b. Conjunctivitis: inflammation of the
Periorbital Cellulitis ... preseptal compartment/orbital ... #pathophysiology ... #ophthalmology ... #diagnosis #signs
Retinoblastoma: Pathogenesis and clinical findings • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Retinoblastoma Signs ... red reflex) • Orbital ... Retinoblastoma #pathophysiology ... #ophthalmology ... #diagnosis #signs
Keratoconus: Pathogenesis and Clinical Findings Genetics • Family history of keratoconus • Ehlers-Danlos syndrome • Down, Turner,
Ehlers-Danlos syndrome ... Turner, Marfan syndromes ... • Rizutti's Sign ... #Keratoconus #pathophysiology ... #ophthalmology
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