The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology diagnosis signs complications urology hyperplasia manifestations ophthalmology pharmacology prostate prostatic adhesivecapsulitis ankylosingspondylitis benzodiazepine bzd cascade cellulitis centralretinalartery crao extraarticular
Inflammatory Cascade: Pathogenesis and Clinical Findings Continued Innate Immunity • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Inflammatory Cascade ... destruction), promote inflammation ... cell activity #Inflammatory ... #Cascade #Inflammation ... pathophysiology #immunology
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings Hormonal alterations (result of aging process) ->
Benign Prostatic ... FGF-related proteins) Inflammation ... activation of inflammatory ... bladder stones #BPH ... #Benign #Prostatic
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
cytokines -> localized inflammatory ... scaling that extend inflammation ... -> Incr local inflammation ... follicles due to inflammation ... diagnosis #signs #symptoms
Periorbital Cellulitis: Pathogenesis and Clinical Findings Definitions: a. Dacryoadenitis: infection of the lacrimal glands b. Conjunctivitis: inflammation of the
Conjunctivitis: inflammation ... Chalazion: a benign ... localized infection or inflammation ... diagnosis #signs #symptoms
Mastoiditis: Pathogenesis and clinical findings Acute or Chronic Otitis Media -> Stage 1: Hyperemeia of the mastoid
mastoid air cells (inflammation ... mucosa leads to inflammation ... mastoid air cells (inflammation ... : Extension of inflammatory ... pathophysiology #signs #symptoms
Benign Prostatic Hyperplasia: Pathogenesis and Medications Aging -> Increased Testosterone -> Testosterone metabolized into DHT by type
Benign Prostatic ... Decreased Prostatic inflammation ... #BPH #Benign
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings • Primary (Idiopathic): Unknown etiology, but associated
shoulder joint inflammation ... as post-inflammatory ... shoulder joint inflammation ... stop, but post-inflammatory ... pathophysiology #diagnosis #symptoms
Mixed Urinary Incontinence: Pathogenesis and Clinical Findings Urgency Urinary Incontinence (UUI) -> Urinary leakage preceded by a
tumour, stone, BPH ... (neurogenic), inflammation ... Pathophysiology #Signs #Symptoms
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
clinical findings • Inflammatory ... viscosity and inflammation ... diagnosis #signs #symptoms
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
• Rate of inflammatory ... etc • Systemic inflammation ... pathophysiology #signs #symptoms
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