The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Distinguishing between Inflammatory and Degenerative joint disease
Inflammatory Joint Disease
 • Swelling stimulates joint nociceptors -> Pain
Lots of fluid, takes ... Swollen Joints • Inflammation ... mild synovial inflammation ... Comparison #Versus #MSK ... #JointDisease #
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
shoulder joint inflammation ... as post-inflammatory ... shoulder joint inflammation ... pathophysiology #diagnosis #symptoms ... #staging #msk
Mastoiditis: Pathogenesis and clinical findings

Acute or Chronic Otitis Media -> 
Stage 1: Hyperemeia of the mastoid
Otitis Media -> Stage ... mucosa leads to inflammation ... are connected) Stage ... : Extension of inflammatory ... pathophysiology #signs #symptoms
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
clinical findings • Inflammatory ... hypercoagulable state ... Hypercoagulable state ... viscosity and inflammation ... diagnosis #signs #symptoms
Ankylosing Spondylitis: Extra-articular Manifestations
 • Ocular - Inflammation of the iris, the anterior part of the
photophobia • GI - Inflammatory ... endoscopy (Not Inflammatory ... • Cardiac - Inflammation ... lung fibrosis #AnkylosingSpondylitis ... diagnosis #signs #symptoms
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings

Hormonal alterations (result of aging process)
    ->
FGF-related proteins) Inflammation ... granulocytes) -> Prostate Inflammation ... activation of inflammatory ... UTIs & bladder stones ... Urology #Signs #Symptoms