The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology diagnosis childhood comparison complications immunization jointdisease jointpain manifestations msk mucocutaneous peds signs sle versus
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
and Degenerative ... Swollen Joints • Inflammation ... Rheumatoid arthritis, Lupus ... mild synovial inflammation ... #Degenerative #
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... cytokines -> localized inflammatory ... Subacute cutaneous lupus ... Phenomenon #Lupus ... diagnosis #signs #symptoms
Childhood Immunization Schedule: Why we immunize • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
Diphtheria Toxin -> URT inflammation ... hemorrhagic rash; symptoms ... Metabolites -> Inflammation ... hepatocellular necrosis & degeneration ... Immunization #peds #pediatrics
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