The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology diagnosis signs symptoms complications allergy hypersensitivityreaction anaphylaxis msk ophthalmology vasculitis lupus manifestations sle stages staging xlinked adhesivecapsulitis agammaglobulinemia allergic
Inflammatory Cascade: Pathogenesis and Clinical Findings Continued Innate Immunity • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Inflammatory Cascade ... cell activity #Inflammatory ... pathophysiology #immunology
Anaphylaxis: Pathogenesis Anaphylaxis is a Type 1 hypersensitivity reaction While the primary mechanism of anaphylaxis is mast cell
production of inflammatory ... Recruitment of inflammatory ... pathophysiology #immunology
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
release the pro-inflammatory ... secretion • Inflammatory ... HypersensitivityReaction #Allergy #Immunology
X-linked Severe Combined Immunodeficiency (SCID): Pathogenesis and clinical findings #SCID #SevereCombinedImmunodeficiency #XLinked #pathophysiology #immunology
pathophysiology #immunology
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
HypersensitivityReaction #Allergy #Immunology
Anaphylaxis: Signs and Symptoms Anaphylaxis: when any egg of three conditions is met: 1. Acute onset of skin/mucosal
pathophysiology #immunology
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
HypersensitivityReaction #Allergy #Immunology
Type II Hypersensitivity: Pathogenesis and clinical findings Definition: When antigens bind to the body's cell surfaces, forming
HypersensitivityReaction #Allergy #Immunology
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
Distinguishing between Inflammatory ... joint disease Inflammatory ... manifestations; positive inflammatory ... physically pushes inflammatory ... by movement #Inflammatory
Anaphylaxis: Treatments (Acute) Additional Info: • IV steroids may be considered for prevention of late phase reactions.
pathophysiology #immunology
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