The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology allergy c5c9deficiency complications humoral hypersensitivityreaction hyperuricemia inflammation inflammatory tophaceous tophi type2
Inflammatory Cascade: Pathogenesis and Clinical Findings Continued Innate Immunity • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Inflammatory Cascade ... Continued Innate Immunity ... dead tissue • Complement ... #Inflammatory #Cascade ... pathophysiology #immunology
Humoral Immunity - Pathogenesis and Clinical Findings Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
Humoral Immunity ... activation • Complement ... contribute to immunity ... exposure #Humoral #Immunity ... pathophysiology #immunology
C5-C9 Deficiency - Pathogenesis and Clinical Findings Note: • Risk of invasive meningococcal disease is 1000-10000x higher
is rare Normal complement ... response: The complement ... cascade -> MAC ... proteins leak out ... pathophysiology #immunology
Gout: Pathogenesis and Clinical Findings - Conditions of rapid cell turnover: hemolysis, psoriasis, lymphoproliferative disorders -
Gout: Pathogenesis ... Activation of complement ... cascade results ... Chronic tophaceous gout ... Complications #Gout
Type II Hypersensitivity: Pathogenesis and clinical findings Definition: When antigens bind to the body's cell surfaces, forming
activates the complement ... cascade, which ... HypersensitivityReaction #Allergy #Immunology
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