The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Post-Traumatic Stress Disorder (PTSD)
Neurochemical abnormalities
 • Hyper-vigilance
 • Emotional hyper-arousal
 • Exaggerated startle reflex
 • Anxiety
startle reflex • Anxiety ... of trauma • Avoidance ... BehavioralDisorder #Pathophysiology ... diagnosis #symptoms #signs ... #psychiatry
Dependent Personality Disorder (DPD): Pathogenesis and Clinical Findings
 • Difficulties with Activities - Initiation Of projects
themselves • Avoidance ... Mnemonic: RELIANCE ... PersonalityDisorder #Diagnosis #Psychiatry ... #Criteria #Signs ... #Symptoms #Mnemonic
Schizotypal Personality Disorder (SPD): Pathogenesis and clinical findings
Cognitive-Perceptual
 • Magical thinking - Belief in paranormal or
Mnemonic: ME PECULIAR ... reference - Anxiety ... PersonalityDisorder #Diagnosis #Psychiatry ... #Criteria #Signs ... #Symptoms #Mnemonic
Borderline Personality Disorder: Pathogenesis and Clinical Findings
Behavioral Traits:
 • Unstable Relationships - Alternating extremes of idealization
/ irritability/anxiety ... experienced BPD ... impairment #BPD ... PersonalityDisorder #Diagnosis #Psychiatry ... #Criteria #Signs
Avoidant Personality Disorder (AVPD): Pathogenesis and Clinical Findings
 • Restraint - Shows excessive restraint in intimate
Avoidant Personality ... others AVPD Mnemonic ... PersonalityDisorder #Diagnosis #Psychiatry ... #Criteria #Signs ... #Symptoms #Mnemonic
Benzodiazepine (BZD) withdrawal: clinical findings and complications

 • Activation of ACC and OFC -> Feelings of
Benzodiazepine ( ... Asthma. or sense of being ... sudden death #Benzodiazepine ... #pharmacology #pathophysiology ... #diagnosis #signs
Panic Disorder: Pathogenesis and clinical findings
Social Factors
 • Parenting and infant attachment
 • Childhood illness/abuse
 •
Experiential Avoidance ... • Avoidance of ... BehavioralDisorder #Pathophysiology ... diagnosis #symptoms #signs ... #psychiatry
Social Anxiety Disorder (SAD) - Pathophysiology 
Excessive fear of one or more social situations
 • Safety
(SAD) - Pathophysiology ... Behaviors and Avoidance ... likelihood of being ... diagnosis #symptoms #signs ... #psychiatry
Opioid Withdrawal: Clinical Findings and Complications
Note: Opioid withdrawal can be extremely uncomfortable, but is rarely life-threatening
life-threatening (exceptions being ... alcohol and/or benzodiazepines ... Dysphoric mood, anxiety ... Withdrawal #Opiate #Pathophysiology ... #Diagnosis #Signs