The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
paresthetica • Symptoms ... sensory • Before diagnosis ... pathophysiology #differential ... #diagnosis #signs ... #symptoms
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
For pituitary masses ... A good mnemonic ... Signs / Symptoms ... Headaches • Nausea ... endocrinology #mnemonic
Borderline Personality Disorder: Pathogenesis and Clinical Findings
Behavioral Traits:
 • Unstable Relationships - Alternating extremes of idealization
severe dissociative symptoms ... experienced BPD Mnemonic ... the above with symptoms ... PersonalityDisorder #Diagnosis ... #Mnemonic #AMSUICIDE
Subjective Tinnitus: Pathogenesis and clinical findings
Subjective Tinnitus - Perceived sound with no acoustic stimulus, heard only
refers to sound caused ... #Tinnitus #Causes ... pathophysiology #differential ... #diagnosis
Schizophrenia: Pathogenesis and Symptoms
Increased dopaminergic transmission in mesolimbic projection
-> Dopaminergic neurons here project into the limbic
Pathogenesis and Symptoms ... is thought to cause ... the Positive Symptoms ... is thought to cause ... pathophysiology #diagnosis
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Alzheimer's (99% of cases ... Alzheimer's (1% of cases ... chromosome 21) Signs / Symptoms ... pathophysiology #geriatrics #diagnosis ... #signs #symptoms
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Diarrhea, Insomnia, Nausea ... gain Incr NE: Nausea ... SideEffects #Psychiatry #Diagnosis ... #Signs #Symptoms
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Equina Syndrome Causes ... spine Signs / Symptoms ... pathophysiology #diagnosis ... #symptoms #signs
Mental Status Exam (MSE)
Note: The MSE is a "snapshot" of a patient at a specific time.
You
You can use the mnemonic ... of illness, the symptoms ... caused by it, and ... MSE #psychiatry #diagnosis ... #evaluation #mnemonic
Schizotypal Personality Disorder (SPD): Pathogenesis and clinical findings
Cognitive-Perceptual
 • Magical thinking - Belief in paranormal or
familiarity SPD Mnemonic ... PersonalityDisorder #Diagnosis ... Criteria #Signs #Symptoms ... #Mnemonic #MEPECULIAR