The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
chromosome 21) Signs / Symptoms ... pathophysiology #geriatrics ... diagnosis #signs #symptoms
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Syndrome Signs/Symptoms ... pathophysiology #peds #pediatrics
Falls: Pathogenesis and Complications
Poly-pharmacy
Disorders affecting movement and balance
 - Sensory deficits
 - Neuromuscular degeneration/Cerebrovascular disease
 -
Lifestyle #Geriatrics
Borderline Personality Disorder: Pathogenesis and Clinical Findings
Behavioral Traits:
 • Unstable Relationships - Alternating extremes of idealization
severe dissociative symptoms ... experienced BPD Mnemonic ... the above with symptoms ... Criteria #Signs #Symptoms ... #Mnemonic #AMSUICIDE
Acute Otitis Media: Pathogenesis and Clinical Findings (in Children)
Upper Respiratory Tract Infection: 
 - Bacterial: Streptococcus
pathophysiology #diagnosis #symptoms ... #signs #peds #pediatrics
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
A good mnemonic ... Signs / Symptoms ... endocrinology #mnemonic
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Signs/Symptoms/Complications ... endocrinology #peds #pediatrics
Fecal Incontinence - Pathogenesis and Complications
Continence mechanisms are impaired
 • Local neuronal damage
 • External and
#Incontinence #geriatrics
Schizotypal Personality Disorder (SPD): Pathogenesis and clinical findings
Cognitive-Perceptual
 • Magical thinking - Belief in paranormal or
familiarity SPD Mnemonic ... Criteria #Signs #Symptoms ... #Mnemonic #MEPECULIAR
Dependent Personality Disorder (DPD): Pathogenesis and Clinical Findings
 • Difficulties with Activities - Initiation Of projects
themselves DPD Mnemonic ... Criteria #Signs #Symptoms ... #Mnemonic #RELIANCE