The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology diagnosis signs symptoms orthopedics complications syndrome allergy immunology fractures sports allergic hypersensitivityreaction injury psychiatry radiology acute anaphylaxis bonetumors causes
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Penicillin-induced drug reaction ... Dermatitis (ie. reaction ... Allergy #Allergic #Reactions ... #Types #Classification
Open Fractures: Mechanisms, Clinical Features and Complications Gustilo-Anderson Classification: • Type I - Wound <
Gustilo-Anderson Classification ... GustiloAnderson #Classification ... Complications #MSK
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications • Anterior Posterior Compression (APC) -
Classification of ... PelvicRing #Fractures #Classification ... #Orthopedics #MSK
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect Examples: Valproate, Carbamazepine, Lamotrigine • Mild anticholinergic effect -> Drowsiness
constipation • Allergic reaction ... mediated cytotoxic reaction
Allergic Rhinitis: Pathogenesis and clinical findings 1. Allergy Sensitization -> Antigen Exposure -> APC (macrophages, HLA class
Primary Reaction ... Secondary Reaction ... after the primary reaction
Representative X-ray appearance of a primary malignant bone tumor - Ewings Sarcoma • "Interrupted periosteal reaction
Interrupted periosteal reaction
Spondylosis - Pathogenesis and Complications Vertebral disease that may compress the vertebral canal from all sides Note: Do
pathophysiology #msk
Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
to an allergic reaction ... causes an immune reaction ... to an allergic reaction ... An allergic reaction ... #Types #Classification
Anaphylaxis: Pathogenesis Anaphylaxis is a Type 1 hypersensitivity reaction While the primary mechanism of anaphylaxis is mast cell
hypersensitivity reaction
Stress Fracture: Pathogenesis and clinical findings Abnormal biomechanics, Repetitive impact activities => Repetitive subthreshold mechanical loading => Bone strain =>
StressFractures #msk
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