The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology peds diagnosis syndrome 21hydroxylasedeficiency 21ohd childhood endocrinology immunization lfcn meralgiaparesthetica orthopedics patellofemoral praderwilli stressfractures
Stress Fracture: Pathogenesis and clinical findings Abnormal biomechanics, Repetitive impact activities => Repetitive subthreshold mechanical loading => Bone strain =>
subthreshold mechanical loading ... from continued loading ... StressFractures #msk ... pathophysiology #symptoms ... #signs
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome Signs ... /Symptoms/Complications ... fractures • Short ... PraderWilli #Syndrome #genetics ... pathophysiology #peds #pediatrics
Patellofemoral Syndrome - Pathogenesis and clinical findings • Anterior Knee Pain with possible symptoms of 'catching'
with possible symptoms ... pain • Palpable grinding ... pathophysiology #diagnosis #signs ... #symptoms #msk
Meralgia paresthetica: Pathogenesis and Clinical Findings Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica •
paresthetica • Symptoms ... MeralgiaParesthetica #MSK ... pathophysiology #differential ... #diagnosis #signs ... #symptoms
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Signs/Symptoms/Complications ... pathophysiology #genetics ... endocrinology #peds #pediatrics
Childhood Immunization Schedule: Why we immunize • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
Tetanus Toxin -> Spores ... hemorrhagic rash; symptoms ... lymph -> Koplik's spots ... non-specific viral symptoms ... Immunization #peds #pediatrics
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