The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Alcohol Use Disorder: Pathogenesis and Clinical Findings

 • Tolerance (reduced sensitivity to effects of EtOH)
 •
craving - Intense ... , tachycardia, nausea ... #Pathophysiology ... #Diagnosis #Signs ... #Symptoms #Psychiatry
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
subthreshold mechanical loading ... from continued loading ... StressFractures #msk ... #orthopedics #pathophysiology ... #symptoms #signs
Panic Disorder: Pathogenesis and clinical findings
Social Factors
 • Parenting and infant attachment
 • Childhood illness/abuse
 •
sweating, trembling, nausea ... exercise, caffeine, alcohol ... BehavioralDisorder #Pathophysiology ... diagnosis #symptoms #signs ... #psychiatry
Alcohol Withdrawal: Clinical Findings and Complications
The onset of alcohol withdrawal generally begins 6-24 hours after the
>2 days after EtOH ... dreams, anorexia, nausea ... #Pathophysiology ... #Diagnosis #Signs ... #Symptoms #EtOH
Social Anxiety Disorder (SAD) - Pathophysiology 
Excessive fear of one or more social situations
 • Safety
Disorder (SAD) - Pathophysiology ... > • Drug and Alcohol ... flashes, headaches, nausea ... diagnosis #symptoms #signs ... #psychiatry
Fracture Healing (and disruptors of this process)
Inflammatory Stage (0-7d)
 • Fracture disrupts local blood vessels ->
- Tobacco & Alcohol ... Fluoroquinolones - Causes ... Healing #Stages #Orthopedics ... #msk #Staging # ... pathophysiology