The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology diagnosis comparison complications ophthalmology agerelated childhood classification diabetes diabetic discherniations endocrinology grades immunization inflammatory injury jointdisease jointpain lowanklesprain maculardegeneration
Low Ankle Sprain: Pathomechanics and Clinical Findings Grading Ligament Sprains l: Minimal ligament disruption, mild swelling & tenderness,
Clinical Findings Grading ... ligament substance leading ... LowAnkleSprain #Sports ... #MSK #orthopedics ... #Grading #Grades
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
Inflammatory and Degenerative ... ESR, RF, ANA) Degenerative ... > Stiffness is short-lived ... #Comparison #Versus ... #MSK #JointDisease
Disc Herniations - Pathogenesis and Complications • 90% of Lumbar disc herniations happen at L4/5 and L5/S1 •
C6/7 Aging ->Degeneration ... -> Mechanical loading ... complications #msk
Childhood Immunization Schedule: Why we immunize • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
Tetanus Toxin -> Spores ... shock • Mumps Virus ... lymph -> Koplik's spots ... vessel collapse leading ... hepatocellular necrosis & degeneration
Diabetic Retinopathy: Pathogenesis and clinical findings Mild Non-proliferative DR • Outpouchings of the weakened capillary walls or
-> Cotton-wool spots ... areas of saccular venous ... retinal ischemia -> Venous ... beading Proliferative
Age Related Macular Degeneration: Pathogenesis and clinical findings Photoreceptor atrophy -> Extracellular debris (drusen) from RPE atrophy/metabolism
Related Macular Degeneration ... blood vessels leak serous ... - Faded/blind spots
Menstrual Cycle Physiology: Correlating the Ovarian and Uterine Cycles Note: Some charts show different relative levels of
days long) • Starts ... follicle (others degenerate ... #UterineCycle #MenstrualCycle
Posterior Cruciate Ligament (PCL) Injury: Pathogenesis and Clinical Findings Classification of PCL Iniuries • Partial: Translation <
Some sort of end ... , - Lachman, - Varus ... + Lachman or + Varus ... #PCL #Injury #MSK ... #Sports #pathophysiology
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